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TYROSINE KINASE, SYK
Descriptors Found:
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DeCS
Descriptor
English
:
Syk Kinase
Descriptor
Spanish
:
Quinasa Syk
Descriptor
Portuguese
:
Quinase Syk
Synonyms
English
:
SYK Tyrosine Kinase
Spleen Tyrosine Kinase
Kinase, SYK Tyrosine
Kinase, Spleen Tyrosine
Kinase, Syk
Tyrosine Kinase, SYK
Tyrosine Kinase, Spleen
Tree Number:
D08.811.913.696.620.682.725.650
D12.644.360.900
D12.776.476.913
Definition
English
:
An SH2 domain-containing non-receptor
tyrosine
kinase that regulates
signal transduction
downstream of a variety of receptors including B-CELL
ANTIGEN
RECEPTORS. It functions in both INNATE
IMMUNITY
and
ADAPTIVE IMMUNITY
and also mediates signaling in
CELL ADHESION
;
OSTEOGENESIS
;
PLATELET ACTIVATION
; and vascular development.
See Related
English
:
src Homology Domains
History Note
English
:
2017 (1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56517
Unique Identifier:
D000072377
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS